Terlipressin acetate rau ESOPHAGAL VARICEEA
Khoom Qhia Qhia
| Lub npe | N- (n- (n-glycylglycyl) glycyl)-l-l-l-l-lysinevasopressin |
| Tus lej | 14636-12-5 |
| Molecular Cov Qauv | C52h74n16o15s2 |
| Molecular hnyav | 1227.37 |
| Einecs tooj | 238-680-8 |
| Kub taw tes | 1824.0 ± 65.0 ° C (kwv yees) |
| Ceev | 1.46 ± 0.1 g / cm3 (kwv yees) |
| Kev Cia | Ua kom tsaus ntuj nti, khw muag khoom hauv lub freezer, hauv qab -15 ° C. |
| Acidity Coefficient | (PMA) 9.90 ± 0.15 (kwv yees) |
Txhais lus hais tias
[N-α-triglycyl-8-Lysine] -vasopressin; 130: PN: Wo2010033207Secid: 171claimpredProutin; 1-triglycyl-8-lysinevasopressin; Nα-glycyl-glycyl-glycyl- [8-Lysine] -vasopressin; Nα-glycyl-glycyl-glycyl-lysine-vasopressin; Nα-glycylglyCylglycyl-vasopressin; Nα-gly-gly-gly-8-lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.
Kev piav txog
Terlipressin, uas nws lub npe tshuaj yog tiglycyllysine vasyopressin, yog qhov tshiab hluavtaws ntev-ua Vasopressin npaj. Nws yog hom kev tawm, uas tsis ua haujlwm ntawm nws tus kheej. Nws yog ua los ntawm Aminopeptidase hauv Vivo kom maj mam "Cov Khoom Siv Lysine Vasopressin tom qab tshem peb glycyl seem ntawm nws n-terminus. Yog li ntawd, terlipressin ua raws li lub pas dej uas tso lysine vasopressin ntawm tus nqi khov kho.
Cov tshuaj pharmacological ntawm terlipressin yog los cog lus cov ntshav du (xws li txo cov ntshav tawm hauv lub portal ntshav ntws thiab portal siab. Ntawm qhov tod tes, nws tseem tuaj yeem txo cov ntshav tawm ntawm cov txiaj ntsig ntawm cov txiaj ntsig ntawm cov nyiaj rov qab, ua kom muaj zog dua thiab cov zis nce ntxiv hauv cov neeg mob Hepitenenal Diamond Syndrome. Terlipressin yog tam sim no tsuas yog cov tshuaj uas tuaj yeem txhim kho tus nqi ciaj sia ntawm cov neeg mob esophageal hawv hemorrhage. Nws yog tsuas yog siv nyob rau hauv kev kho mob kho mob ntawm vliceal hemorrhage. Tsis tas li ntawd, Terlipressin tseem tau ua tiav zoo nyob hauv daim siab thiab raum. Feem ntau, nws zoo li yuav mus ua txoj haujlwm tau txais txiaj ntsig hauv Coexisting Refractory Shock thiab Cardiopulmonary resuscitation. Piv nrog vasopressin, nws muaj cov nyhuv ntev ntev, suav nrog kev phom sij ntev, thiab yooj yim siv (kev saib xyuas kom haum thiab kev saib xyuas tseem ceeb. Kev cawm seej thiab kev kho mob ntawm cov neeg mob tsis zoo.
