Desmopressin Acetate kho mob plawv mob ntshav qab zib insipidus
Product Detail
| Lub npe | Desmopressin |
| CAS nr | 16679-58-6 |
| Cov mis mos molecular | C46H64N14O12S2 |
| Molecular hnyav | 1069.22 Nws |
| EINECS Number | 240-726-7 ib |
| Kev sib hloov tshwj xeeb | D25 + 85.5 ± 2 ° (xws li peptide dawb) |
| Qhov ntom | 1.56 ± 0.1 g / cm3 (Kev kwv yees) |
| RTECS No. | YW9000000 |
| Cia tej yam kev mob | Khaws ntawm 0 ° C |
| Solubility | H2O: soluble 20mg / mL, ntshiab, tsis muaj xim |
| Acidity coefficient | (pKa) 9.90 ± 0.15 (Predicted) |
Synonyms
MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2;MINIRIN;[DEAMINO1, DARG8] VASOPRESSIN;[DEAMINO-CYS1, D-ARG8]-VASOPRESSIN;DDAVP, HUMAN;DESMOPRESSIN;DESMOPRESSIN, HUMAN;DESAMINO-[D-ARG8] VASOPRESSIN
Cov lus qhia
(1) Kev kho mob plawv mob ntshav qab zib insipidus.Tom qab cov tshuaj tuaj yeem txo cov zis tso zis, txo cov zis zaus thiab txo qhov nocturia.
(2) Kev kho mob ntawm nocturnal enuresis (cov neeg mob hnub nyoog 5 xyoos lossis tshaj saud).
(3) Ntsuam xyuas lub raum tso zis muaj nuj nqi, thiab ua kom paub qhov txawv ntawm lub raum ua haujlwm.
(4) Rau hemophilia thiab lwm yam kab mob los ntshav, cov khoom no tuaj yeem txo lub sijhawm los ntshav thiab tiv thaiv los ntshav.Nws tuaj yeem txo tus nqi ntawm cov ntshav intraoperative poob thiab postoperative oozing;tshwj xeeb tshaj yog ua ke nrog kev tswj hwm cov ntshav siab thaum lub sijhawm phais, nws tuaj yeem txo qis cov ntshav los ntawm cov txheej txheem sib txawv, thiab txo qis tom qab kev phais, uas tuaj yeem ua lub luag haujlwm zoo dua hauv kev tiv thaiv ntshav.
Kev kho mob ntshav qab zib insipidus
Mob ntshav qab zib insipidus feem ntau yog ib qho teeb meem ntawm cov dej metabolism hauv cov zis ntau dhau, polydipsia, hypoosmolarity, thiab hypernatremia.Ib feem lossis ua tiav qhov tsis txaus ntawm vasopressin (central diabetes insipidus), lossis lub raum tsis txaus ntawm vasopressin (nephrogenic diabetes insipidus) tuaj yeem tshwm sim.Clinically, ntshav qab zib insipidus zoo ib yam li thawj polydipsia, ib qho mob uas tau txais cov kua dej ntau dhau los ntawm kev ua haujlwm tsis zoo ntawm cov txheej txheem tswj lossis nqhis dej tsis zoo.Contrary to thawj polydipsia, qhov nce hauv dej kom tsawg hauv cov neeg mob ntshav qab zib insipidus yog cov lus teb sib xws rau kev hloov pauv hauv osmotic siab lossis ntshav ntim.
