Lub npe | Vancomycin |
CAS nr | 1404-90-6 |
Cov mis mos molecular | C66H75Cl2N9O24 |
Molecular hnyav | 1449.25 Nws |
EINECS Number | 215-772-6 ib |
Qhov ntom | 1.2882 (kev kwv yees kwv yees) |
Refractive Index | 1.7350 (kwv yees) |
Cia tej yam kev mob | Muab ntim rau hauv qhuav, 2-8 ° C |
Vancomycin(baseand/orunspecifiedsalts);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-( 3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-10,19-dichloro-2,3,4,5, 6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino) )-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno -1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylicacid.
Vancomycin yog ib qho tshuaj tua kab mob glycopeptide.Nws cov txheej txheem ntawm kev ua yog khi nrog kev sib raug zoo siab rau alanylalanine ntawm poly-terminal kawg ntawm precursor peptide ntawm cov kab mob rhiab cell phab ntsa, thaiv cov synthesis ntawm macromolecular peptidoglycan uas tsim cov kab mob ntawm phab ntsa, uas ua rau kev puas tsuaj ntawm tes. phab ntsa tua cov kab mob.Vancomycin siv tau rau cov kab mob loj uas tshwm sim los ntawm cov kab mob Gram-zoo, tshwj xeeb tshaj yog cov uas tshwm sim los ntawm methicillin-resistant Staphylococcus aureus, Staphylococcus epidermidis, thiab Enterococcus uas tiv taus lwm yam tshuaj tua kab mob los yog tsis zoo.
Nws yog txwv rau cov kab mob uas tshwm sim los ntawm methicillin-resistant Staphylococcus aureus (MRSA) thiab kab mob hauv plab thiab kab mob hauv lub cev los ntawm Clostridium difficile;penicillin-allergic cov neeg mob tsis tuaj yeem siv penicillins lossis cephalosporins hauv cov neeg mob uas muaj tus kab mob staphylococcal hnyav, lossis cov neeg muaj tus kab mob staphylococcal hnyav uas tsis teb rau cov tshuaj tua kab mob saum toj no, vancomycin tuaj yeem siv.Cov khoom no kuj yog siv rau kev kho mob ntawm Enterococcus endocarditis thiab Corynebacterium (Diphtheria-zoo li) endocarditis nyob rau hauv cov neeg tsis haum rau penicillin.Kev kho mob ntawm staphylococcus-induced arteriovenous shunt kab mob hauv cov neeg mob hemodialysis ua xua rau penicillin thiab tsis ua xua rau penicillin.