Carbetocin los tiv thaiv Uterine Contraction thiab Postpartum Hemorrhage
Product Detail
| Lub npe | CARBETOCIN |
| CAS nr | 37025-55-1 |
| Cov mis mos molecular | C45H69N11O12S |
| Molecular hnyav | 988.17 ib |
| EINECS Number | 253-312-6 |
| Kev sib hloov tshwj xeeb | D -69.0 ° (c = 0.25 hauv 1M acetic acid) |
| Boiling point | 1477.9 ± 65.0 ° C (Predicted) |
| Qhov ntom | 1.218 ± 0.06 g / cm3 (Kev kwv yees) |
| Cia tej yam kev mob | -15 ° C |
| Daim ntawv | hmoov |
Synonyms
BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2, (SULFIDEBONDBETWEENBUTYRYL-4-YLANDCYS);BUTYRYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-LEU-GLY-NH2TRIFLUOROACETATESALT;(BUTYRYL1, TYR(ME)2)-1-CARBAOXYTOC INTRIFLUOROACETATESALT;(BUTYRYL1, TYR(ME)2)-OXYTOCIN;(BUTYRYL1,TYR(ME)2)-OXYTOCINTRIFLUOROACETATESALT;CARBETOCIN;CARBETOCINTRILUOROACETATESALT;(2-O-methyltyrosine)-DE-Amino-1-CARBAOXYTOCIN
Kev ua si lom neeg
Carbetocin, ib qho oxytocin (OT) analog, yog oxytocin receptor agonist nrog Ki ntawm 7.1 nM.Carbetocin muaj affinity siab (Ki = 1.17 μM) rau lub chimeric N-terminus ntawm oxytocin receptor.Carbetocin muaj peev xwm rau kev tshawb fawb tom qab yug me nyuam.Carbetocin tuaj yeem nkag mus rau hauv cov ntshav-hlwb teeb meem thiab muaj kev ua haujlwm zoo li kev ntxhov siab los ntawm kev ua kom oxytocin receptors hauv CNS.
Muaj nuj nqi
Carbetocin yog ib qho hluavtaws ua haujlwm ntev oxytocin 8-peptide analog nrog cov khoom agonist, thiab nws cov khoom siv tshuaj kho mob thiab tshuaj zoo ib yam li cov oxytocin tshwm sim.Zoo li oxytocin, carbetocin khi rau cov tshuaj hormones receptors ntawm lub tsev menyuam cov leeg nqaij, ua rau lub tsev menyuam muaj zog, ua rau nws zaus thiab nce lub suab ntawm lub tsev menyuam raws li kev cog lus ntawm qhov qub.Oxytocin receptor theem nyob rau hauv lub tsev menyuam yog tsawg nyob rau hauv lub xeev tsis cev xeeb tub, nce thaum cev xeeb tub, thiab ncov thaum lub sij hawm cev xeeb tub.Yog li ntawd, carbetocin tsis muaj kev cuam tshuam rau lub tsev menyuam uas tsis yog cev xeeb tub, tab sis muaj lub zog uterine contractile effect ntawm lub tsev menyuam cev xeeb tub thiab lub tsev menyuam tshiab.
Hloov Cov Tswj
Kev hloov pauv raug tswj raws li tus txheej txheem.Raws li qhov cuam tshuam thiab kev pheej hmoo thiab qhov hnyav, kev hloov pauv tau muab faib ua Loj, Me thiab Qhov Chaw.Cov kev hloov pauv ntawm qhov chaw muaj kev cuam tshuam me ntsis rau kev nyab xeeb thiab zoo ntawm cov khoom, thiab yog li tsis xav tau kev pom zoo thiab ceeb toom rau tus neeg siv khoom;Cov kev hloov me me muaj feem cuam tshuam rau kev nyab xeeb thiab zoo ntawm cov khoom, thiab yuav tsum tau ceeb toom rau cov neeg siv khoom;Cov kev hloov loj muaj kev cuam tshuam ntau dua rau kev nyab xeeb thiab cov khoom zoo, thiab xav tau kev pom zoo los ntawm cov neeg siv khoom.
Raws li cov txheej txheem, kev hloov pauv yog pib nrog kev hloov pauv hauv daim ntawv thov uas hloov cov ntsiab lus thiab kev xav txog kev hloov pauv tau piav qhia.Kev ntsuam xyuas yog tom qab ntawd ua raws li daim ntawv thov, uas yog ua los ntawm kev hloov pauv tswj cov chaw haujlwm.Lub caij no, kev tswj kev hloov pauv tau muab faib ua Qib Loj, Qib General thiab Qib Me.Tom qab kev ntsuam xyuas tsim nyog nrog rau kev faib tawm, txhua theem kev hloov pauv yuav tsum tau pom zoo los ntawm QA Tus Thawj Coj.Kev tswj hwm kev hloov pauv tau ua tiav tom qab kev pom zoo raws li txoj kev npaj ua.Kev tswj hwm kev hloov pauv thaum kawg raug kaw tom qab QA lees paub qhov kev hloov pauv tau raug coj los siv.Yog tias muaj kev ceeb toom rau tus neeg siv khoom, tus neeg siv yuav tsum tau ceeb toom raws sijhawm tom qab kev hloov pauv tau pom zoo
