Ganirelix acetate peptide API

Cov lus piav qhia luv luv:

Lub npe: Ganirelix acetate

Tus lej lej: 123246-29-7

Cov Qauv Molecular: C80H113Cln18o13

Molecular hnyav: 1570.34

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Khoom Qhia Qhia

Lub npe	Ganirelix acetate
Tus lej	123246-29-7
Molecular Cov Qauv	C80H113Cln18o13
Molecular hnyav	1570.34

Txhais lus hais tias

AC-Dnal-DCPA-DPAL-DPAL-DPAL-DPAL-DPAL-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr-Tyr Ganirelix; Ganirelix acetate USP / EP /

Kev piav txog

Ganirelix yog cov khoom hluavtaws extthetide, thiab nws cov acetate ntsev, gonirelix acetate yog gonadotropin-tso cov tshuaj hormones (gonrh) relector tiv thaiv. Cov amino acid se yog: AC-D-2NAL-D-4CPA-D-4CPA-D-3PAL-D-Homoarg (9,10-et2) -pro-d- ala-nh2. Feem ntau yog kho, nws yog siv nyob rau hauv cov poj niam tau pab txhawb kev ua me nyuam Luteinizing kev ua kom muaj kev cuam tshuam ntxov thiab kho cov xeeb ceem vim qhov no. Cov tshuaj muaj cov yam ntxwv ntawm cov kev sib raug zoo uas tsis muaj kev nyuaj siab thiab lub sijhawm muaj txiaj ntsig luv luv, thiab muaj cov txiaj ntsig luv luv piv nrog cov tshuaj sib xws hauv kev coj ua.

Pharmacological txiav txim siab

Lub pulsatile tso cov gonadotropin-tso cov hormones (GNRH) stimulates synthesis thiab tso zais ntawm lh thiab fsh. Zaus ntawm LH pulses nyob rau hauv nruab nrab thiab lig follicular kaujsees yog kwv yees li 1 ib teev. Cov kab mob no tau raug cuam tshuam hauv kev hloov siab nce siab hauv cov ntshav dej lh. Thaum nruab nrab-coj khaub ncaws, qhov loj tshaj tawm ntawm GNRH ua rau muaj kev tawm ntawm LH. Lub Midmenstrual LH Surge tuaj yeem ua rau muaj cov lus teb ntawm lub cev, suav nrog: ovulation, ocyte kev rov pib dua. Qhov tsim ntawm Corpus Luteum ua sawv progesterone qib sawv, thaum Estradiol qib poob. Ganirelix acetate yog GNRH kev thaiv av uas tau sib tw nrog cov khoom siv gonadoughs thiab cov kev hloov chaw. Nws ua rau muaj kev tiv thaiv nrawm nrawm, thim rov qab ntawm gonadotropin zais cia. Tus inisitos cov nyhuv ntawm Ganirelix acetate ntawm pituitary lH excition muaj zog dua li ntawm FSH. Ganirelix acetate ua tsis tiav rau kev tso tawm thawj zaug tso tawm ntawm endogenous gonadotropins, sib thooj nrog kev thaiv kev. Ua kom tiav rov qab ntawm pituitary lh thiab qib FSH tau tshwm sim tsis pub dhau 48 teev tom qab Ganirelix acetate tau txiav tawm.

Yav dhau los: Cetrorelix acetate kom tiv thaiv kev ua kom ntxov ovulation 120287-85-6

Tom ntej: Li li linaclopotide rau cov plab zom mov hauv plab hnyuv 851199-59-2

Sau koj cov lus ntawm no thiab xa mus rau peb