Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU yog ib qho hluavtaws lipidated linker molecule tsim los rau kev xa tshuaj thiab tshuaj tiv thaiv kab mob-tshuaj conjugates (ADCs). Nws nta stearoyl (Ste) hydrophobic tail, γ-glutamyl lub hom phiaj motif, AEEA spacers rau qhov yooj, thiab OSu (NHS ester) pab pawg kom muaj txiaj ntsig zoo.

 
Kev Tshawb Fawb & Kev Siv:

Siv nyob rau hauv tsom prodrug synthesis thiab nanocarrier tsim

Txhim kho cell membrane kev sib cuam tshuam thiab kev siv tshuaj

Ua kom yooj yim rau qhov chaw tshwj xeeb payload txuas rau peptides, tshuaj tiv thaiv kab mob, lossis cov neeg nqa khoom

Khoom nta (Gentolex Group):

High purity, npaj-rau-conjugate NHS ester

Haum rau bioconjugation thiab kev tshawb fawb xa tawm

Ste-γ-Glu-AEEA-AEEA-OSU yog qhov zoo tagnrho rau kev txhim kho kev siv tshuaj zoo.