ua Tuam Tshoj Paclitaxel 33069-62-4 Anti-tumor Botanical Tshuaj rau Ovarian Cancer, Mis Cancer Hoobkas thiab manufacturers |Gentolex
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Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Mob cancer mis Featured duab
  • Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer
  • Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer

Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer

Lus piav qhia luv luv:

Melting point: 213 ° C

Kub taw tes: 774.66 ° C (kwv yees ntxhib)

Kev sib hloov tshwj xeeb: D20 -49 ° (methanol)

Qhov ceev: 1.0352 (nruab nrab kwv yees)

Lub teeb taw tes: 9 ° C

Cia txias: 2-8 ° C

Daim ntawv: hmoov

Acidity coefficient: 11.90 ± 0.20 (Predicted)

Xim: Dawb


Product Detail

Khoom cim npe

Product Detail

Lub npe Paclitaxel
CAS nr 33069-62-4
Cov mis mos molecular C47H51NO14
Molecular hnyav 853.92 ib
EINECS Number 608-826-9
Boiling Point 774.66 ° C (Tshaj tawm)
Qhov ntom 0.200 Nws
Kev cia khoom Muab ntim rau hauv qhuav, Khaws rau hauv lub freezer, 2-8 ° C
Daim ntawv Hmoov
Xim Dawb
Ntim PE hnab + Aluminium hnab

Synonyms

Paclitaxel HCL; Paclitaxel (natural crude); Paclitaxelx; N-BENZYL-BETA-PHENYLISOSERINE ESTER; PACLITAXEL, TAXUS BREVIFOLIA; PACLITAXEL, TAXUS SPECIES; PACLITAXOL; PACLITAXEL

Pharmacological nyhuv

Kev piav qhia

Paclitaxel yog monomeric diterpenoid muab rho tawm los ntawm cov tawv ntoo ntawm cov nroj tsuag ntuj Taxus tshuaj.Isotope tracing pom tias paclitaxel tsuas yog khi rau polymerized microtubules thiab tsis hnov ​​​​mob nrog unpolymerized tubulin dimers.Tom qab cov hlwb raug rau paclitaxel, ntau cov microtubules yuav raug sau rau hauv cov hlwb.Lub tsub zuj zuj ntawm cov microtubules cuam tshuam nrog ntau yam kev ua haujlwm ntawm cov hlwb, tshwj xeeb tshaj yog kev faib cell nres nyob rau theem mitotic thiab thaiv qhov kev faib tawm ntawm cov hlwb.Los ntawm Ⅱ-Ⅲ kev tshawb fawb soj ntsuam, paclitaxel feem ntau yog tsim rau cov qog nqaij hlav zes qe menyuam thiab mob qog noj ntshav, thiab tseem muaj qee yam kev kho mob rau mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav thiab lub caj dab, qog nqaij hlav thiab lub hlwb.

 

Cov lus qhia

Nws muaj cov txiaj ntsig zoo hauv kev kho mob qog noj ntshav ntawm zes qe menyuam thiab platinum thiab lwm yam qog nqaij hlav zes qe menyuam thiab mob qog noj ntshav.Mob qog noj ntshav, mob qog noj ntshav sab sauv, cov cell me thiab cov qog nqaij hlav tsis me me muaj qhov pom zoo.

 

Kev siv

Siv 1: Broad-spectrum anti-tumor botanicals rau zes qe menyuam qog noj ntshav, mob cancer mis, thiab lwm yam.

Siv 2: broad-spectrum anti-tumor botanicals rau kev kho mob ntawm zes qe menyuam, mob cancer mis thiab lwm yam kab mob.

Siv 3: tshuaj tiv thaiv kab mob.Rau kev kho mob cancer mis metastatic thiab mob qog noj ntshav ntawm zes qe menyuam.Broad-spectrum anti-tumor botanicals rau kev kho mob ntawm zes qe menyuam, mob cancer mis thiab lwm yam kab mob.

Siv 4: Siv tshuaj tiv thaiv qog noj ntshav;khi rau N-terminal thaj tsam ntawm β-tubulin, txhawb kev ruaj khov microtubule qub, tiv thaiv depolymerization, tiv thaiv kev sib faib ntawm tes thiab cuab rau hauv G2 / M theem ntawm lub voj voog ntawm tes.

Siv 5: Cov tshuaj tiv thaiv microtubule, inhibiting depolymerization los ntawm kev txhawb nqa tubulin polymerization, tswj tubulin stability, thiab inhibiting cell mitosis.

 

 

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