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Chondroitin sulfate rau kev kho mob plawv caj dab, mob caj dab thiab kho mob ntawm pob txha caj dab 98%

Cov lus piav qhia luv luv:

CAS TSIS MUAJ .: 9007-28-7

Cov Qauv Molecular: C13h2No15s

Molecular hnyav: 463.36854

Einecs Tsis muaj.: 232-696-9

Daim Ntawv: Hmoov

Xim: Dawb rau off-dawb

Dej Solubility: Soluble hauv dej

Purity: 98%


Khoom Qhia Qhia

Khoom Ntawv

Khoom Qhia Qhia

Lub npe Chondroitin Sulfate
Tus lej 9007-28-7
Molecular Cov Qauv C13h2no15s
Molecular hnyav 463.36854
Einecs tooj 232-696-9
Dej solubility Soluble hauv dej
Kev coj dawb huv 98%
Chaw ntim khoom Khw ntawm cov ntsuas kub ib txwm
Puab Hmoov
Xim Dawb rau off-dawb
Yam ntim PE hnab + Aluminium Hnab

Txhais lus hais tias

Poly-1 (2/3)-Acetyl-2-amino-2-deexy-3-o-beta-d-beta-d-beta-d-beta-d-beta-d-beta-3-o-beta-3-(6) Chondroitinpoly sulfate; chondroitin sulfates; Chondroiti nsulfuricacid; Chondroitin sulfuric acids; chonsurid; CSO; 5ξ) -2- (60-deoxyamino) -2-deoxy-3-O-β-d-glucopyranl-4-O-sulfo-l-arabino-hexopyranose

Pharmacological effect

Kev piav txog

Chondroitinsulfate (CS) yog ib qho acidic mucopolysaccharide extracted thiab huv los ntawm cov tsiaj pob txha mos ntim. Chondroitin sulfate muaj cov qauv sib txawv xws li A, C, B, H thiab K. Cov nqaij mos, tawv nqaij, tawv nqaij, thiab lwm yam. Cov ntsiab lus ntawm cov ntses pob txha mos yog cov nplua nuj heev, xws li 50% mus rau 60% hauv cov pob txha shark, thiab tsawg heev hauv cov ntaub so ntswg sib txuas.

Rau tus kab mob npaws atherosclerotic, nce ntshav, cov roj (cholesterol), angina pectoris, myocardial infarction, thiab lwm yam hauv cov neeg mob plawv.

 

Pharmacological txiav txim siab

RapamyCy (Rapa) muaj cov kev mob zoo sib xws rau FK506. Nyob rau hauv ib tug loj ntawm cov kev sim tshuaj mob, nws cov kev mob tshwm sim tau pom kom muaj koob tshuaj tiv thaiv thiab rapa ntawm kho nepotoxicity thiab tsis muaj kev sib tw hingperplasia. Lub ntsiab mob lom thiab cov kev mob tshwm sim muaj: mob taub hau, xeev siab, kiv taub hau, taub ntswg, thiab mob sib koom tes. Kuaj cov khoom lag luam, tsis ntev los no, hypomagnese dezymia, istchacemia, hypomagnesemia, thiab lwm yam tawv muag istema, thiab lwm yam tawv muag Kev tswj hwm, thiab qhov ua rau muaj cov ntshav phosphamate qis yog xav ua lub raum ntev los ntawm lub raum ntev los ntawm rapa-raws li immunosuppressive kev kho. Zoo li lwm tus immunosuppressants, SCA tau muaj kev kis tau tus kab mob ntau ntxiv los ua mob ntsws, tab sis qhov tshwm sim ntawm lwm yam kev sib txawv tsis txawv ntawm CSA.

 

Kev Txom Nyem Kev Phem

Chondroitin sulfate dav muaj nyob rau hauv tib neeg thiab tsiaj pob txha mos ntim. Kev npaj noj tshuaj feem ntau muaj ob qho isomers ntawm chondroitin sulfate a thiab chaondroitin sulfate c, thiab cov ntsiab lus ntawm chondroitin sulfage ntawm cov tsiaj ntawm cov tsiaj sib txawv thiab cov hnub nyoog sib txawv. Nws cov teebmeem ntawm cov twj twj yog raws li hauv qab no: Chondroitin sulfate tuaj yeem tshem tawm cov ntshav thiab cov roj chotheroscleros, thiab ua kom cov roj choports) thiab nce cov roj ntsha thiab cov rog hauv cov hlwb. Chondroitin sulfate tuaj yeem tiv thaiv thiab kho mob plawv. Nws muaj anti-atherosclerosis thiab anti-heri-atherogenic plaque tsim kev cuam tshuam ntawm kev sim arteriosclerosis qauv; Ua kom cov ceg sib daj sib xyaw ua ke lossis cov sib xyaw ntawm atherosclerosis, thiab tuaj yeem nrawm coronary arteriosclerosis lossis embolism. Kho, rov tsim dua tshiab thiab kho ntawm myocardial necrosis lossis degeneration. Nws tuaj yeem nce biosynthes ntawm xov tooj ntawm tes ribonucleic acid (mrna) thiab muaj cov txiaj ntsig ntawm kev txhawb nqa cov metabolism hauv lub metabolism. Tsis tshua anticoagulant kev ua si. Chondroitin sulfate muaj kev cuam tshuam txog kev tawm tsam, thiab txhua 1 mg ntawm chondroitin sulfate ib qho yog sib npaug rau cov kev ua ub no ntawm 0.45u ntawm hepwinin. Qhov kev ua yeeb yam anticoagulant tsis yog nyob ntawm Antithromombin III los ua nws lub luag haujlwm, nws tuaj yeem ua rau antert anticoagulant kev ua si los ntawm Fibrinogen System. Chondroitin sulfate kuj muaj los tiv thaiv kev ua kom zoo, kho kom nrawm dua kho kom zoo thiab tiv thaiv cov qog.


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