Lub npe | Kev sib tham |
Tus lej | 396-01-0 |
Molecular Cov Qauv | C12h11N7 |
Molecular hnyav | 253.26 |
Einecs tooj | 206-904-3 |
Kub taw tes | 386.46 ° C |
Kev coj dawb huv | 98% |
Chaw ntim khoom | Kaw Hauv Qhuav, Chav Chav |
Puab | Hmoov |
Xim | Daj ntseg daj rau daj |
Yam ntim | PE hnab + Aluminium Hnab |
6-phenymas-; 7-pteridinetriamine, 6-phenyl-4; Diren; Diurene; Dyren; DYTAC
Lub ntsiab
TriagleMterene yog cov poov xab-spareting diuretic, uas muaj cov diuretic cuam tshuam ntawm kev khaws cov poov tshuaj thiab cov tshuab ntawm kev ua yog txawv. Nws tseem muaj cov nyhuv diuretic tom qab inhibiting aldosterone tso zais nrog sodium chloride lossis tshem cov caj pas adrenal. Nws qhov chaw ua haujlwm yog nyob rau hauv distal concoluted tripute, inhiberming kev sib pauv ntawm sodium thiab potassium ions, nce cov zis, thiab txo qhov kev ua yeeb yam ntawm K +. Nws tseem tuaj yeem tiv thaiv lub reabroorption ntawm na + thiab kev zais ntawm k + los ntawm kev sau duct. Cov nyhuv diuretic ntawm cov khoom no tsis muaj zog. Thaum siv ua ke nrog diuretics xws li thiazide xws li, nws tsis tuaj yeem ua rau muaj kev cuam tshuam zoo ntawm cov tshuaj lom neeg tshwm sim los ntawm Potassium excretion ntawm tom kawg. Ib qho ntxiv, tseem muaj cov nyhuv ntawm excreting uric acid. Kev siv ntev ntev tuaj yeem nce cov ntshav urera. Nws yog tsuas yog siv rau kev txhawb nqa edractable edema lossis ASCES tau tshwm sim los ntawm lub plawv tsis ua haujlwm, mob siab ua siab thiab mob nusritis. Nws kuj tseem siv tau rau cov neeg mob uas tsis muaj txiaj ntsig nrog hydrochlorothand lossis spironolactone.
Pharmacological effect
Cov khoom no yog cov poov xab-sparing diuretic, uas sib txig sib luag ntawm na +, cl-, thiab dej, thaum txo cov excretion ntawm K +.
Kev taw qhia
Nws yog tsuas yog siv rau kev kho mob ntawm Edema Cov Kab Mob; suav nrog lub plawv dhia ua tsis tiav, lub siab ua siab ascites thiab dej thiab sodium dettrential thaum lub sijhawm kho adrenant glucocorticoids; Nws kuj tseem siv tau rau kev kho ntawm idiopathic edema.
Kev siv
Lub zog diuretic. Cov nyhuv yog sai thiab luv luv, Diuresis pib 2 teev tom qab kev tswj xyuas qhov ncauj, mus txog qhov kawg ntawm 6 teev, thiab cov nyhuv kav 8-12 teev. Nws yog clinically siv rau intractable edema lossis ascites tshwm sim los ntawm lub plawv tsis ua haujlwm, mob siab rau lub siab, thiab tseem siv rau hydrochlorothide lossis spironolactone lossis spironolactone. . Cov khoom no muaj cov nuj nqi ntawm tshem tawm cov kua roj acid thiab haum rau kev kho mob ntawm gout.