RU-58841 Siv los tiv thaiv plaub hau thiab txiv neej txawv Baldness
Product Detail
| Lub npe | UA-58841 |
| CAS nr | 154992-24-2 |
| Cov mis mos molecular | C17H18F3N3O3 |
| Molecular hnyav | 369.34 ib |
| EINECS Number | 1592732-453-0 |
| Boiling Point | 493.6 ± 55.0 ° C (Predicted) |
| Qhov ntom | 1.39 ib |
| Kev cia khoom | Muab ntim rau hauv qhuav, Khaws rau hauv lub freezer, hauv qab -20 ° C |
| Daim ntawv | Hmoov |
| Xim | Dawb |
| Ntim | PE hnab + Aluminium hnab |
Synonyms
RU58841; 4-(4,4-Dimethyl-2,5-dioxo-3-(4-hydroxybutyl)1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile; onitrile; 4-[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl)ben zonitrile; RU-58841E: candyli (at) speedgainpharma (dot) com; CS-637; RU588841; RU58841; RU58841; RU-58841
Pharmacological nyhuv
Kev piav qhia
RU 58841 (PSK-3841) yog ib qho androgen receptor antagonist uas txhawb cov plaub hau regrowth.RU58841 yog ib qho tshuaj tshawb nrhiav uas tsim los rau kev kho mob ntawm androgenic alopecia, tseem hu ua txiv neej qauv baldness (MPD).
Raws li cov tshuaj pleev ib ce anti-androgen, nws txoj cai ntawm kev ua tsis zoo ib yam li finasteride. Finasteride ncaj qha ua rau 5α reductase, inhibits kev hloov pauv ntawm testosterone rau hauv DHT, thiab txo cov ntsiab lus ntawm DHT hauv lub cev. RU58841 thaiv kev sib cuag ntawm dihydrotestosterone thiab cov plaub hau follicle receptors, nws tsis ncaj qha txo DHT cov ntsiab lus, tab sis nws txo qhov kev khi ntawm DHT thiab cov plaub hau follicle receptors, thiaj li ua tiav lub hom phiaj ntawm kev kho androgenetic alopecia.
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl) benzonitrile tuaj yeem siv los ua cov tshuaj chemical synthesis intermediates.Yog hais tias 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile tau nqus, Txav tus neeg mob mus rau qhov cua ntshiab;Nyob rau hauv rooj plaub ntawm kev sib cuag ntawm daim tawv nqaij, tshem tawm cov khaub ncaws tsis huv, ntxuav cov tawv nqaij kom huv si nrog xab npum thiab dej, thiab nrhiav kev kho mob yog tias tsis xis nyob;
Sab nyhuv
RU58841 yog siv rau ntawm tawv taub hau, nqus los ntawm cov hauv paus plaub hau, thiab theoretically, nws tuaj yeem nkag mus rau hauv cov hlab ntsha thiab cuam tshuam rau lwm qhov ntawm lub cev. Tab sis tsis muaj cov kev mob tshwm sim tshwm sim hauv cov kev tshawb fawb ntawm cov tshuaj pleev ib ce hauv cov liab. Txawm li cas los xij, qee cov neeg uas tau sim RU58841 hais tias lawv tau ntsib qee qhov kev mob tshwm sim los ntawm kev siv RU, suav nrog cov tawv nqaij khaus, txo libido, erectile kawg, xeev siab, qhov muag liab, kiv taub hau, thiab mob taub hau.
