RU-58841 siv los ua cov plaub hau tiv thaiv thiab cov txiv neej txawv tawv
Khoom Qhia Qhia
| Lub npe | Ru-58841 |
| Tus lej | 154992-24-2 |
| Molecular Cov Qauv | C17h18f3n3o3 |
| Molecular hnyav | 369.34 |
| Einecs tooj | 1592732-453-0 |
| Kub taw tes | 493.6 ± 55.0 ° C (kwv yees) |
| Ceev | 1.39 |
| Chaw Cia Khoom | Muab ntim rau hauv qhuav, khaws rau hauv lub freezer, hauv qab -20 ° C |
| Puab | Hmoov |
| Xim | Xim dawb |
| Yam ntim | PE hnab + Aluminium Hnab |
Txhais lus hais tias
Ru58841; 4- (4,4-Dadethyl-2,5-Dioxo-3- (4-Hydroxybutyl) 1-iMidazolidinyl) -2- (Trifluorrethyl) Benzo nitrile; 4- [3- (4-Hydroxybutyl) -4,4-Dadethyl-2,5-Dioxo-1-imidazolidinyl] -2- (trifluorrethyl) benz onitrile; 4- [3- (4-Hydrothbutyl) -4,4-Dadethyl-2,5-dioxoimidazolidin-1-YL] -2- (trifluoromethyl) ben Zoniturile; Ru-588411e: CAND CYLI (AT) SUDGIEFA (DOT) SH; CS-637; RU58841; RU58841; RU-58841
Pharmacological effect
Kev piav txog
RU 58841 (Psk-3841) yog ib qho Androgen receptor kev thaiv av uas txhawb nqa plaub hau regrowth.RU58841 yog kev tshawb xyuas cov tshuaj tsim kev kho mob rau kev kho cov alopecia, tseem hu ua txiv neej qauv ua yeeb yam (MPD).
Raws li cov tshuaj pleev ib ce tawm los tiv thaiv, nws txoj ntsiab lus ntawm kev nqis tes ua tsis zoo ib yam li cov finnium. Taslaside Ua ncaj qha ua rau 5α reductase, inhibits hloov dua siab tshiab ntawm Testosterone rau DHT, thiab txo cov ntsiab lus ntawm DHT hauv lub cev. RU58841 blocks tiv toj ntawm dihydrotestosterone thiab cov plaub hau follictenors, tab sis nws tsis ncaj qha txo cov ntsiab lus DHT thiab cov plaub hau ntawm kev kho lub hom phiaj ntawm Androgenetic alopecia.
4- [[3- (4-Hydroxybutyl) -4,4-Dadethyl-2,5-Dioxo-1-iMidazalrile) Benzonitrile Benthesis Intermediates.Yog 4- [3- (4-hydroxThaum muaj kev sib chwv tawv nqaij, tshem tawm cov khaub ncaws tsis huv, yaug cov tawv nqaij kom huv si nrog xab npum thiab dej, thiab nrhiav kev kho mob yog tias tsis xis nyob;
Sab cuam
RU58841 tau thov rau saum tawv taub hau, nqus cov hauv paus, thiab theoretically, nws tuaj yeem nkag mus rau hauv cov hlab ntshav thiab cuam tshuam lwm qhov ntawm lub cev. Tab sis tsis muaj cov kev mob tshwm sim hauv cov kev mob tshwm sim hauv kev tshawb fawb ntawm daim ntawv thov cov phiajcim hauv liab. Txawm li cas los xij, qee tus neeg uas tau sim ua Ru58841 thov kom lawv tau txais kev phiv los ntawm kev siv RU, nrog rau lub qhov muag qis, txo qis muag, kiv taub hau, thiab mob taub hau.
