Pegcetacoplan

Pegcetacoplan API

Pegcetacoplan yog ib qho pegylated cyclic peptide uas ua raws li lub hom phiaj C3 ntxiv inhibitor, tsim rau kev kho mob ntawm cov kab mob sib ntxiv xws li paroxysmal nocturnal hemoglobinuria (PNH) thiab thaj chaw atrophy (GA) hauv cov hnub nyoog ntsig txog macular degeneration.

Mechanism & Kev Tshawb Fawb:
Pegcetacoplan khi kom ntxiv cov protein C3 thiab C3b, tiv thaiv kev ua kom lub plab ntxiv. Qhov no txo:
Hemolysis thiab o hauv PNH
Retinal cell puas nyob rau hauv geographic atrophy
Immune-mediated ntaub so ntswg raug mob nyob rau hauv lwm yam complement-driven disorders