Mecobalamin yog rau kev kho mob ntawm peripheral hlab ntsha cuam tshuam
Khoom Qhia Qhia
| Lub npe | Mecobalamin |
| Tus lej | 13422-55-4 |
| Molecular Cov Qauv | C63h90Con13O14P |
| Molecular hnyav | 1343.4 |
| Melting taw tes | > 190 ° C (Dec.) |
| So | DMOs (me ntsis), methanol (sparingly), dej (me ntsis) |
| Kev coj dawb huv | 99% |
| Chaw ntim khoom | Muab ntim rau hauv qhuav, khaws rau hauv lub freezer, hauv qab -20 ° C |
| Puab | Khov kho |
| Xim | Tsaus liab |
| Yam ntim | PE hnab + Aluminium Hnab |
Txhais lus hais tias
Mecobalamin; Mecobalamine; Cobalcobalamin; Cobalcobalamin; estyl-yaj, ester-metyllbenazolylcobalamin; vitamin B12; Algobaz
Pharmacological effect
Muaj nuj nqis ua haujlwm
Methylcobalamin yog tshuaj rau kev kho mob ntawm cov hlab ntsha tsis sib haum xeeb. Piv nrog rau lwm cov vitamin B12 npaj, nws muaj qhov hloov tau zoo rau cov leeg ntaub so ntswg. Nws tuaj yeem txhawb nucleic acid-protein-lipid metabolism hauv methyl conversion kev tiv thaiv thiab kho cov ntaub so ntswg puas. Nws yog lub luag haujlwm ntawm coenzyme nyob rau hauv cov txheej txheem ntawm synthesizing metionsine ntawm synthesationine, tshwj xeeb tshaj yog txhawb nqa cov khoom siv dag zog, thiab txhawb nqa cov xwm txheej ntawm DNA thiab RNA. Tsis tas li ntawd, hauv kev sim cov glial hlwb ua rau cov kev ua phem thiab txhawb nqa cov synthesis ntawm myelin liipid lecithin. Txhim kho cov metabolic cuam tshuam ntawm cov leeg metabolic tuaj yeem txhawb nqa cov hluavtaws thiab lawv cov protein ntau, ua rau cov pob txha ceev, thiab tswj hwm kev ua haujlwm ntawm cov txhuas. Methylcobalamin Kev txhaj tshuaj kuj tseem tuaj yeem cuam tshuam qhov txawv txav ntawm cov hlab ntaws, txhawb nqa lub zog thiab faib ua eremria. Methylcobalamin muaj peev xwm rov kho cov ntshav liab suav, hemoglobin, thiab hemalisins tus nas uas tau raug txo vim b12 tsis muaj peev xwm. Siv rau megaloblastic anemia thiab peripheral hlab ntsha cuam tshuam los ntawm qhov tsis muaj vitamin B12.
Pharmacological effect
Methylcobalamin yog qhov kev sib tw ntawm vitamin B12. Nws muaj npe tom qab nws cov qauv tshuaj. Nws yuav tsum tau hu ua "methyl vitamin B12". Nws tuaj yeem txhawb cov metabolism ntawm cov rog, txhawb cov hluavtaws ntawm Lecithy hauv Schwann cov hlwb, thiab txhim kho cov leeg ua kom zoo nkauj; Nws tuaj yeem nkag ncaj qha nkag mus rau cov hlab ntsha hlwb thiab txhawb qhov kev tsim kho ntawm cov xeb uas raug puas; Tsim kho cov synhein synthesis ntawm cov hlab hlwb, ntxiv dag zog axon anabolism anabolism, tiv thaiv kev ua tsis ncaj oob khab; Koom nrog nucleic acid synthesis, txhawb hematopoietic muaj nuj nqi. Clinically, feem ntau nws yog feem ntau siv nyob rau hauv kev kho mob ntshav qab zib neuropathy, thiab nws cov nyhuv ntev kuj muaj qee cov nyhuv ntawm cov hlab ntshav ntawm cov ntshav ntshav qab zib. Methylcobalamin yog tsuas yog siv rau cov kab mob neurologal ntawm cov kabmob ntshav qab zib thiab megaloboftictance anemia tshwm sim los ntawm qhov tsis muaj vitamin B12. Nws yog dav siv kev kho mob nrog qee qhov kev mob tshwm sim.
Kev siv
Nws yog siv los kho cov kab mob kom huv, txo qhov mob thiab loog thiab ua kom muaj kev mob nkeeg, thiab kho kev lag luam tam sim no, thiab lwm yam.
