Deflazacort muaj anti-inflammatory, anti-filgic, thiab nce gluconeogenesis cuam tshuam
Khoom Qhia Qhia
| Lub npe | Deflazacort |
| Tus lej | 14484-47-0 |
| Molecular Cov Qauv | C25h31no6 |
| Molecular hnyav | 441.52 |
| Einecs tooj | 238-483-7 |
| Kub taw tes | 595.4 ± 50.0 ° C |
| Kev coj dawb huv | 98% |
| Chaw ntim khoom | Kaw Hauv Qhuav, Chav Chav |
| Puab | Hmoov |
| Xim | Xim dawb |
| Yam ntim | PE hnab + Aluminium Hnab |
Txhais lus hais tias
16-D) Oxazole-3,20-dione, 11-Dihyrdoxy-2'-5'-beta-h-peta-h-peta-h-peta-h-peta-h-peta-h-peta-h-peta-h-pegin; 11β-hydroxy-21-acetyloxy-2'-Methyl-1,2,4,5-tetradehydrognano [17,16-d] Oxazole-3,20-acetee -21-acetyroxy-11β-hydroxy -2'-Methylpregnano [17,16-d] Oxazole-1,4-diene-3,20-dione; 11b, 21-dihydroxy-2 '-; thiab Denazacort
Pharmacological effect
Kev taw qhia
Txog thawj cov tub rog uas tsis paub txog, tshuaj tiv thaiv kab mob Hematasietic, tsis muaj tshuaj rau cov neeg mob ntsws, thiab ua xua rau cov tuberculosietic
Cov kev ceev faj
(1) zoo li lwm cov glucocorticoids, nws yog contraindicated rau cov kab mob sib kis tau.
(2) Siv nrog kev ceeb toom, lub plab zom mov, lub raum tsis ua hauj lwm, cov ntshav qab zib, myasthenia gravis thiab lwm yam kab mob. Cev xeeb tub thiab ua kom cov poj niam uas siv tau nrog kev ceev faj.
Cov Tshuaj Sib Tham
1. Deflazacort muaj cov tshuaj potassium excretion effect, yog li kev saib xyuas yuav tsum tau noj thaum nws siv ua ke nrog diuretics.
2. Thaum siv hauv kev sib xyaw nrog cov tshuaj nrog enzymatic kev txiav txim (Rifampaticin, phenobarbital, thiab lwm yam), glucocorticoids yuav tsum tau nce siab.
3. Erythromycin thiab estrogen tuaj yeem inhibit lub metabolism tuaj yeem inhibit cov metabolism thiab cov tshuaj nquag, thiab cov tshuaj yuav tsum raug txo kom tsawg thaum siv ua ke. Tshuaj lom neeg cov khoom acetone-hexane crystallization, melting point 255-256.5 ℃. [α] d + 62.3 ° (c = 0.5, chloroform).
Kev siv
Cov GLUCOCORDICS muaj los tiv thaiv kev tiv thaiv, tiv thaiv kev ua xua, thiab nce gluconeogenesis cuam tshuam. Txog thawj tus kab mob tsis txaus, kab mob collemenism, cov kab mob hemativ, femerative tub rog, hematopoetic malignancies, thiab lwm yam.
