Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Daim ntawv thov tshawb fawb:
Qhov kev tiv thaiv tetrapeptide no yog siv rau hauv peptide synthesis thiab conformational kev tshawb fawb. Kev koom ua ke ntawm Aib (α-aminoisobutyric acid) tso cai rau cov kws tshawb fawb los tshawb xyuas cov qauv helical thiab folding tus cwj pwm hauv luv peptides. Cov pab pawg tiv thaiv kev ua haujlwm (Boc, Trt) ua kom muaj kev ruaj ntseg thiab kev xaiv thaum lub sij hawm sib zog-theem peptide synthesis, ua rau nws yog ib qho qauv zoo rau kev kawm peptide caj qaum dynamics thiab kev sib cuam tshuam ntawm kev sib txuas.

Muaj nuj nqi:
Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH ua tus qauv sib xyaw rau kev tshawb nrhiav peptide stability thiab cov qauv tsim. Aib pab txhawb rau helical stabilization, thaum histidine thiab glutamine residues muab cov chaw muaj peev xwm sib cuam tshuam, muaj txiaj ntsig zoo hauv kev tsim cov peptides bioactive los yog ua cov protein ntau. Nws kuj tuaj yeem ua tus thawj coj rau kev ua haujlwm peptides hauv kev txhim kho tshuaj lossis tshuaj biochemical.