Retatrutide yog ib qho kev tawm tsam ntau tus receptor agonist, feem ntau yog siv los kho cov rog rog thiab cov kab mob metabolic. Nws tuaj yeem ua rau tib lub sijhawm qhib peb lub incretin receptors, suav nrog GLP-1 (glucagon-zoo li peptide-1), GIP (glucose-dependent insulinotropic polypeptide) thiab glucagon receptor. Cov txheej txheem ntau yam no ua rau retatrutide pom muaj peev xwm zoo hauv kev tswj qhov hnyav, tswj ntshav qab zib thiab kev noj qab haus huv tag nrho.
Cov yam ntxwv tseem ceeb thiab cov teebmeem ntawm retatrutide:
1. Ntau lub tshuab ua haujlwm:
(1) GLP-1 receptor agonism: Retatrutide txhawb nqa insulin secretion thiab inhibits glucagon tso tawm los ntawm activating GLP-1 receptors, yog li pab txo cov ntshav qab zib, qeeb plab hnyuv thiab txo qab los noj mov.
(2) GIP receptor agonism: GIP receptor agonism tuaj yeem txhim kho qhov tso tawm ntawm insulin thiab pab txo cov ntshav qab zib ntxiv.
2. Glucagon receptor agonism: Glucagon receptor agonism tuaj yeem txhawb cov rog decomposition thiab lub zog metabolism, yog li pab kom poob phaus.
3. Cov txiaj ntsig poob ceeb thawj: Retaglutide tau qhia qhov hnyav hnyav hauv cov kev tshawb fawb soj ntsuam thiab tshwj xeeb tshaj yog rau cov neeg mob rog lossis cov neeg mob metabolic syndrome. Vim nws ntau yam kev ua haujlwm, nws muaj kev ua tau zoo hauv kev txo lub cev rog thiab tswj qhov hnyav.
4. Kev tswj ntshav qab zib: Retaglutide tuaj yeem txo cov ntshav qab zib kom zoo thiab tshwj xeeb tshaj yog rau cov neeg mob ntshav qab zib hom 2 uas xav tau kev tswj ntshav qab zib. Nws tuaj yeem pab txhim kho kev nkag siab ntawm insulin thiab txo qis cov piam thaj hauv ntshav tom qab hloov pauv.
5. Kev noj qab haus huv hauv plawv: Txawm hais tias cov tshuaj retaglutide tseem nyob rau theem kev tshawb fawb soj ntsuam, cov ntaub ntawv thaum ntxov qhia tau tias nws yuav muaj peev xwm txo qis kev pheej hmoo ntawm cov hlab plawv, zoo ib yam li kev tiv thaiv kab mob plawv ntawm lwm cov tshuaj GLP-1.
6. Kev tswj hwm kev txhaj tshuaj: Retaglutide tam sim no yog tswj hwm los ntawm kev txhaj tshuaj subcutaneous, feem ntau yog siv sijhawm ntev ib lub lis piam ib zaug, thiab qhov kev siv tshuaj ntau zaus pab txhim kho kev ua raws li tus neeg mob.
7. Cov kev mob tshwm sim: Cov kev mob tshwm sim muaj xws li cov tsos mob ntawm plab hnyuv xws li xeev siab, ntuav thiab raws plab, zoo ib yam li cov kev mob tshwm sim ntawm lwm cov tshuaj GLP-1. Cov tsos mob no muaj ntau dua nyob rau theem pib ntawm kev kho mob, tab sis cov neeg mob feem ntau maj mam hloov raws li lub sij hawm kho mob nce.
Kev tshawb nrhiav thiab kev siv tshuaj kho mob:
Retaglutide tseem tab tom raug kev sim tshuaj loj, feem ntau los ntsuas nws cov teebmeem mus ntev thiab kev nyab xeeb hauv kev kho mob rog. Cov txiaj ntsig ntawm kev soj ntsuam thaum ntxov qhia tau hais tias cov tshuaj muaj txiaj ntsig zoo rau kev poob phaus thiab txhim kho kev noj qab haus huv ntawm metabolic, tshwj xeeb tshaj yog rau cov neeg mob uas muaj kev txwv tsis pub siv tshuaj.
Retaglutide yog suav tias yog ib hom tshuaj peptide tshiab uas muaj peev xwm siv tau zoo hauv kev kho mob rog, metabolic syndrome thiab hom 2 mob ntshav qab zib. Nrog rau kev tshaj tawm cov ntaub ntawv soj ntsuam ntau ntxiv yav tom ntej, nws xav tias yuav dhau los ua lwm yam tshuaj rau kev kho mob rog thiab kab mob metabolic.
Post lub sij hawm: May-27-2025