Fitusiran

Fitusiran (API)

Daim ntawv thov tshawb fawb:
Fitusiran API yog ib qho hluavtaws me me cuam tshuam RNA (siRNA) tau tshawb xyuas feem ntau hauv thaj tsam ntawm hemophilia thiab coagulation disorders. Nws aims lubAntithrombin (AT lossis SERPINC1)gene nyob rau hauv lub siab kom txo tau cov tshuaj antithrombin. Cov kws tshawb fawb siv Fitusiran los tshawb txog RNA cuam tshuam (RNAi) cov txheej txheem, lub siab tshwj xeeb ntawm cov gene silencing, thiab cov tswv yim kho tshiab rau rebalancing coagulation hauv cov neeg mob hemophilia A thiab B, nrog lossis tsis muaj inhibitors.

Muaj nuj nqi:
Fitusiran ua haujlwm los ntawm kev ua kom lub ntsej muag ntawm cov tshuaj antithrombin, ib qho tshuaj tiv thaiv kab mob ntuj, yog li ua rau thrombin tiam thiab txhawb kev tsim cov ntshav. Cov txheej txheem no muab txoj hauv kev kho mob prophylactic los txo qis los ntshav hauv cov neeg mob hemophilia. Raws li API, Fitusiran ua haujlwm ua cov khoom muaj nyob rau hauv kev kho mob subcutaneous ntev txhawm rau txhim kho lub neej zoo thiab txo qis kev kho mob hauv cov hlab ntshav.